Buy AB-CHMINACA Crystal online
Buy AB-CHMINACA crystal also 1-(cyclohexylmethyl)-1H-indazole-3- carboxamide. (AB-CHMINACA). is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB1 receptor (Ki = 0.78 nM) and CB2 receptor (Ki = 0.45 nM) and fully substitutes for ?9-THC in rat discrimination studies, while being 16x more potent.Buy AB-CHMINACA Crystal online
synthesis of (S)-AB-CHMINACA has been described byLongworth et al. (Longworth et al., 2016). The synthesis of (S)-AB-CHMINACA described by Longworth et al., started with 1H-indazole-3-carboxylic acid, which was subjected to Fischer esterification to give the corresponding methyl ester (methyl 1H-indazole-3-carboxylate). Alkylation of the ester with the appropriate bromoalkane ((bromomethyl) cyclohexane), in the presence of potassium tert-butoxide produced methyl 1-(cyclohexylmethyl)-1H-indazole-3- carboxylate. Saponification of the ester gave the acid 1-(cyclohexylmethyl)-1H-indazole-3-carboxylic acid, which was then reacted with l-valinamide to produce (S)-AB- CHMINACA (Longworth et al., 2016).(R)-AB-CHMINACA could also be synthesised under identical conditions, using D-valinamide instead of l-valinamide. Using valinamide would produce racemic AB-CHMINACA
(Moosmann et al., 2017). According to Buchler et al. (Buchler at al., 2009) the starting compound methyl 1H-indazole-3-carboxylate, which is commercially available, can be prepared from 1H-indole-2,3- dione (Johnson and Rodgers, 2005). In summary, potential precursors of AB-CHMINACA are
1H-indole-2,3-dione (20), 1H-indazole-3-carboxylic acid, methyl 1H-indazole-3-carboxylate, l-valinamide (for the synthesis of the (S)-enantiomer), valinamide for the racemic AB-CHMINACA and (bromomethyl)cyclohexane.3.8.2 The mode and scope of the esta.
AB-CHMINACA is a synthetic cannabinoid and a CB1 receptor agonist. It shares some pharmacological similarities with Δ9-tetrahydrocannabinol (THC), which is responsible for the major psychoactive effects of cannabis. In humans, AB-CHMINACA appears to cause effects that resemble
those of cannabis and other synthetic cannabinoids. AB-CHMINACA has been available in the European Union since at least February 2014. It has been detected in 24 Member States, Turkey and Norway. More than 4 000 seizures have been made within the European Union, which
includes 43 kg of powder and 40 kg of herbal material which has been laced with AB-CHMINACA. This herbal material is typically sold as smoking mixtures; the products are marketed as ‘legal’ replacements to cannabis. Due to the way that these products are produced, it appears that users are at risk of serious poisoning.Buy AB-CHMINACA Crystal online http://authenticchemicals.com/